Statistical design
In connection with Norecopa's Annual General Meeting on 11 June 2009, Dr. Manuel Berdoy from Oxford University gave three lectures on the theme of "Statistics: The Good, The Bad and The Ugly".
These lectures covered the essence of statistical thinking when planning animal experiments (p values, power analysis, determination of sample size, experimental design, analyses and control of variation) and ways to implement Reduction and Refinement.
His lecture notes can be downloaded here.
Manuel Berdoy is co-author of The Design of Animal Experiments: Reducing the Use of Animals in Research Through Better Experimental Design:
Reviews of the book are available here.
An interactive CD based on this book has also been produced:
Topics covered on the CD include:
Choice of animal model; The experimental unit; Applying valid statistics; Improving precision; Increasing the range of applicability; Planning and organising; Self-assessment activity; Software tools and references.
Isogenic.info: a website on statistics compiled by Michael Festing. The site consists of sections on:
A statistical guide for authors, produced by the journal Animal.
Online courses arranged by the University of Oxford, including statistics training and data analysis.
Principles of Experimental Design for the Life Sciences by Murray R. Selwyn
Guidelines for the design and statistical analysis of experiments using laboratory animals
Sample size determination and Estimating animal numbers, from the Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research (2003)
These lectures covered the essence of statistical thinking when planning animal experiments (p values, power analysis, determination of sample size, experimental design, analyses and control of variation) and ways to implement Reduction and Refinement.
His lecture notes can be downloaded here.
Manuel Berdoy is co-author of The Design of Animal Experiments: Reducing the Use of Animals in Research Through Better Experimental Design:
Reviews of the book are available here.
An interactive CD based on this book has also been produced:
Topics covered on the CD include:
Choice of animal model; The experimental unit; Applying valid statistics; Improving precision; Increasing the range of applicability; Planning and organising; Self-assessment activity; Software tools and references.
Isogenic.info: a website on statistics compiled by Michael Festing. The site consists of sections on:
- Design (15 steps in the design and statistical analysis of experiments involving laboratory animals)
- Isogenic strains (inbred and F1 animals)
- Animal models
- Genetics and toxicity testing
A statistical guide for authors, produced by the journal Animal.
Online courses arranged by the University of Oxford, including statistics training and data analysis.
Principles of Experimental Design for the Life Sciences by Murray R. Selwyn
Guidelines for the design and statistical analysis of experiments using laboratory animals
Sample size determination and Estimating animal numbers, from the Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research (2003)
Foto: colourbox.com