Guidelines A-Z
This is a collection of guidelines, produced by Norecopa in cooperation with the Norwegian Reference Centre for Laboratory Animal Science and Alternatives. Neither Norecopa or the Reference Centre necessarily endorse the content of the literature in this list, which is offered at face value as a service to the research community. Please report any broken links. Suggestions for additions or deletions are also welcome.
Amphibians
Blood removal
Cancer research
Carbon dioxide
Health monitoring
Humane endpoints
Veterinary Care
A comprehensive overview of guidelines, databases and information centres was published in 2005:
Administration of substances
Agricultural animals
Smith AJ & Allen T (2005): Animal Welfare 14:347-359.
Administration of substances
- Refining procedures for the administration of substances
- A good practice guide to the administration of substances and removal of blood, including routes and volumes
Agricultural animals
- UKCCCR Guidelines for the Use of Cell Lines in Cancer Research
- Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching
Amphibians
- Information Resources on Amphibians, Fish & Reptiles Used in Biomedical Research
- Guidelines for use of live amphibians and reptiles in field research (ASIH)
- Guidelines on Antibody Production, from the Canadian Council on Animal Care (CCAC).
- CCAC policy statement on Acceptable Immunological Procedures.
Blood removal
- Removal of blood from laboratory mammals and birds
- Saphenous vein puncture for blood sampling of mouse, rat, hamster, gerbil, guinea pig, ferret and mink
- A good practice guide to the administration of substances and removal of blood, including routes and volumes
Cancer research
- An overview of guidelines for the use of animals in cancer research
- Guidelines for the welfare and use of animals in cancer research
Carbon dioxide
- Concerns about Carbon Dioxide Use in Euthanasia and Anesthesia (HSUS report)
- Newcastle Consensus Meeting on Carbon Dioxide Euthanasia of Laboratory Animals, 27th-28th February 2006
- CCAC Categories of Invasiveness in Animal Experiments. A policy statement produced by the Canadian Council on Animal Care.
- Conclusions of an EU expert group on severity classification of scientific procedures performed on animals
- The use of databases, information centres and guidelines when planning research that may involve animals.
- Smith AJ & Allen T (2005): Animal Welfare 14:347-359.
- A list of reference resources produced by AAALAC International
- A list of guidelines assembled by the Institutional Animal Care and Use Committee, University of Florida
- NIH Design Policy and Guidelines for Clinical Centres, Research Laboratories and Animal Facilities
- Guidelines for Planning and Design of Biomedical Research Laboratory Facilities
- FELASA guidelines for training technicians, researchers and specialists
- Guidelines for Humane Education: Alternatives to the Use of Animals in Teaching and Training
- The Role of Computational Models in Animal Research
- Principles and Guidelines for the Use of Animals in Precollege Education
- Ethics training for licensees
Ethical review
- Guidelines on Animal Use Protocol Review, from the Canadian Council on Animal Care (CCAC).
- Guidelines for the operation of institutional animal care and use committees in the UK
- FELASA working group report on ethical review principles and practice in Europe
- Documents for laypeople on ethics committees, produced by the RSPCA (Royal Society for the Protection of Animals), UK.
- Paper on Cost-Benefit Review (2003) Animal Procedures Committee, UK
- Documents for laypeople on ethics committees, Royal Society for the Protection of Animals (RSPCA), UK
- Retrospective reviews of animal experiments
- Guidance notes on Retrospective Review: A discussion document prepared by the LASA Ethics and Training Group
- Guidelines for the Use of Fishes in Research
- Guidelines for the Use of Wild Fish in Field Research
- Information Resources on Amphibians, Fish & Reptiles Used in Biomedical Research
- Species-specific provisions for fish in the European Convention for the protection of animals used for experimental and scientific purposes (presentation at a meeting in Oslo in May 2005)
- Canadian Guidelines for the care & use of fish in research, teaching and testing (presentation at a meeting in Oslo in May 2005)
- Guidelines on: the care and use of fish in research, teaching and testing from the Canadian Council on Animal Care (CCAC)
- Guidelines for health and welfare monitoring of fish used in research
- Information Resources on Fish Welfare, compiled by AWIC (Animal Welfare Information Center, United States Department of Agriculture)
- Care and use of fish as laboratory animals: Current state of knowlege (1998)
- Fish related IACUC web resources, compiled by the USDA
- Responsible Care And Health Maintenance Of Fish In Commercial Aquaculture
- Fish Research and the Institutional Animal Care and Use Committee
- A survey of animal care considerations for fish handling
- The zebrafish book. A guide for the laboratory use of zebrafish (Danio rerio)
- Zebrafish Information Network
- Aquatic Animal Health Code
- Care of fish in biological research
- CCAC guidelines on transgenic animals
- Refinement and reduction in production of genetically modified mice
- Sharing and archiving of genetically modified mice
Health monitoring
- FELASA guidelines for health monitoring
- Implications of infectious agents on results of animal experiments
Humane endpoints
- Proceedings of two International Conferences on the Use of Humane Endpoints in Animal Experiments for Biomedical Research
- Humane endpoints in laboratory animal experimentation
- CCAC guidelines on choosing an appropriate endpoint in experiments using animals for research, teaching and testing
- Recommendations for euthanasia of experimental animals: Part 1
- Recommendations for euthanasia of experimental animals: Part 2
- Newcastle consensus meeting on carbon dioxide euthanasia of laboratory animals
- AVMA Guidelines on Euthanasia (previously called The 2000 Report of the AVMA Panel on Euthanasia
- Guidelines for the Euthanasia of Nondomestic animals, produced by the American Association of Zoo Veterinarians
- Advancing refinement of laboratory animal use
- Refinement of mouse husbandry
- Refinement in rabbit husbandry
- Refinements in laboratory bird husbandry and procedures
- Refining dog husbandry and care
- Guidance on the rehoming of laboratory dogs
- Information Resources on the Care and Welfare of Rabbits
- Report of the 2002 RSPCA/UFAW meeting (7.8 MB) (reproduced with permission from Animal Technology and Welfare)
- Guidance and Codes of Practice from the Home Office, UK, relating to the Animals (Scientific Procedures) Act 1986
- Guidelines on the operation of The Animals (Scientific Procedures) Act, UK
- Guiding Principles on the Supervision Requirements for Personal Licensees
- Aide Memoir for the preparation of Project Licence Abstracts
- Guide for the Care and Use of Mammals in Neuroscience and Behavioral Research
- Key considerations in the breeding of macaques and marmosets for scientific purposes
- Quick reference paper on laboratory animal feeding and nutrition. Report from the FELASA working group.
- A UK report on Recognizing and Assessing Pain, Suffering and Distress
- Guidelines for the Recognition and Assessment of Animal Pain
- Ethical Guidelines for Investigations of Experimental Pain in Conscious Animals produced by the International Association for the Study of Pain (IASP)
- FELASA report on Pain and distress in laboratory rodents and lagomorphs
- Uniform Requirements for Manuscripts submitted to Biomedical Journals (Vancouver konvensjonen)
- Guidelines for reporting the results of experiments using mammals
- Guidelines for reporting the results of experiments using fish
- The ARRIVE guidelines for reporting animal research
- Reporting the Severity of Animal Procedures Retrospectively
- Guidelines for reporting statistical data
- Guidelines for use of live amphibians and reptiles in field research (ASIH, 1987)
- Information Resources on Amphibians, Fish & Reptiles Used in Biomedical Research
- Refinements in telemetry procedures
- Husbandry refinements for rats, mice, dogs and non-human primates used in telemetry procedures
Veterinary Care
- Guidelines for the provision of Adequate Veterinary Care for Laboratory Animals from the American College of Laboratory Animal Medicine
- Guidelines for the Capture, Handling and Care of Mammals, from the American Society of Mammalogists
- Guidelines on the Care and Use of Wildlife, from the Canadian Council on Animal Care (CCAC)
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